Sunday, November 22, 2015

PET Perfusion Tracers


Rb-82
N13 ammonia
T 1/2
75 secs
10 mins
Dose/Injection Rate
20mCi
Bolus <30secs
BGO/LSO/GSO scanners
10-20mCi
Bolus <30secs
Extraction Mechanism
Na/K ATPase pump
Extraction decreases with increasing blood flow
Can be decreased by hypoxia, acidosis and ischemia
Na/K transporter
Passive diffusion
Type of stress used
Pharm stress
(short t1/2 of Rb, patient needs to remain still in camera)
Pharm stress
Imaging delay after injection
EF>50%: 70-90secs
EF <50%: 90-130 secs
1.5-3mins
Imaging duration
3-6 mins
10-15 mins
Reconstructed pixel size
4 mm
2-3 mm
Organ receiving maximum dose
Kidney
Urinary bladder

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